Cognitive Scaffold

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MENTAL MODEL · M8808

Multiple Hypothesis Testing

Multiple Hypothesis Testing
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Updated 2026-08-15

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INTRODUCTION

English translation pending.

CORE DEFINITION

When many hypotheses are tested at once, the chance of at least one false positive grows with the number of tests, so a nominal significance threshold no longer controls error at its stated level, and with a thousand tests a significant result becomes almost certain by chance alone. Statistical practice therefore adjusts either the family-wise error rate, as in the Bonferroni correction, or the false discovery rate. The qualification is that adjustment trades power for control, so the choice depends on whether a single false claim or a mixed set of claims is more costly.

SCAFFOLDING EFFECT

psychology

Reduce cognitive load

- Use Result Skepticism: ask how many comparisons were run before believing a single significant finding. - Use Threshold Selection: choose family-wise or false discovery control based on the cost of a false claim.

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Anchor fast decisions

Each test carries its own small error probability, and those probabilities accumulate across comparisons, so with enough tests a significant result becomes almost certain by chance alone. Adjustment raises the bar per test so that the combined error rate returns to the intended level.

MINIMUM ACTION

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Source support: Explicit

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    en.wikipedia.orghttps://en.wikipedia.org/wiki/Multiple_comparisons_problemZH · Explicit
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