Muller's Ratchet
Version 1.0.0 · Updated 2026-07-30
CORE DEFINITION
In asexual populations, deleterious mutations accumulate irreversibly (like a ratchet that only turns one way), leading to an ever-increasing genetic load and eventual extinction. Sexual reproduction (genetic recombination) can purge these deleterious mutations.
SCAFFOLDING EFFECT
Reduce cognitive load
Degeneration of closed systems. A closed organization or ideological system, lacking external genetic exchange (recombination), accumulates internal errors and toxins unidirectionally like a ratchet, unable to self-cleanse. Openness and exchange are the only mechanisms to purge systemic toxins.
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Asexual populations lack genetic recombination, so deleterious mutations accumulate unidirectionally (ratchet only goes forward, not backward), increasing genetic load until extinction; sexual reproduction uses recombination to purge mutations, achieving self-cleaning.
MINIMUM ACTION
In progress 0/1Practice this model in one real situation:
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Source support: Explicit
- en.wikipedia.orghttps://en.wikipedia.org/wiki/Muller%27s_ratchetverified
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