Stopping Rule
Updated 2026-08-10
INTRODUCTION
English translation pending.
CORE DEFINITION
In sequential analysis and clinical trials, a stopping rule defines the evidence state at which data collection ends. Group-sequential designs express it as boundaries, such as the O'Brien-Fleming or Pocock boundaries, that permit early stopping while holding the overall type I error rate at its nominal level. The key constraint is timing: the rule must be set before the data are seen, because a rule chosen or revised after peeking inflates false positives and distorts p-values and confidence intervals.
SCAFFOLDING EFFECT
Reduce cognitive load
- Fix it early: Write the sample size, effect threshold and stopping condition before collecting any data. - Correct for peeking: Use sequential boundaries whenever you must look at the data more than once. - Honour the trigger: Stop when the condition is met instead of continuing to justify sunk cost.
Anchor fast decisions
Every unplanned look at accumulating data is an extra test, so the chance of a false positive grows with the number of looks. A stopping rule counters this by distributing the total error budget across the planned analyses, so each interim check uses a stricter threshold and the overall error rate stays fixed. Pre-specification is what makes the result interpretable, because the boundary no longer depends on the data it judges.
MINIMUM ACTION
In progress 0/1Practice this model in one real situation:
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Source support: Explicit
- en.wikipedia.orghttps://en.wikipedia.org/wiki/Stopping_timeverified
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